This webinar gathers global experts to discuss the evolving role of non-invasive prenatal testing (NIPT) in twin and multiple pregnancies. The session explores test performance, limitations, and practical recommendations for screening in complex multifetal scenarios.
Presenters review the clinical implications of cell-free DNA testing in both dizygotic and monozygotic twins, as well as triplet and higher-order gestations. Topics include the impact of fetal fraction, chorionicity, and the number of fetuses on test accuracy—particularly for trisomy 21 and other common aneuploidies.
The webinar also addresses ethical and counseling challenges unique to multiple pregnancies, such as discordant results, inconclusive findings, and follow-up strategies. Panelists stress the need for careful communication, informed consent, and multidisciplinary support when interpreting NIPT results in multifetal contexts.
Case examples highlight diagnostic dilemmas and reinforce the role of ultrasound as a complementary tool in early screening. Discussions also touch on emerging research, technical limitations, and future directions for improving test reliability.
This session offers valuable insights into the current and future role of NIPT in twin and multiple pregnancies, supporting clinicians in delivering accurate, compassionate, and individualized prenatal care.
For related clinical discussions, watch the session on fetal intervention in twin and multiple pregnancy: challenging cases.
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