This clinical report evaluates the diagnostic performance of quantitative ultrasound (QUS) technologies, Tissue Attenuation Imaging (TAI™) and Tissue Scatter Distribution Imaging (TSI™), using the Samsung RS85 Prestige ultrasound system for the assessment of hepatic steatosis in nonalcoholic fatty liver disease (NAFLD). Affecting roughly 25% of the global population, NAFLD can progress to advanced liver diseases, making accurate, noninvasive diagnostics crucial.
In a study conducted by Jeon et al. at Seoul National University Hospital, 173 participants with suspected NAFLD underwent QUS examinations with Samsung’s RS85 Prestige system alongside MRI-PDFF as the reference standard. The research assessed the diagnostic accuracy of TAI™ and TSI™ across three stages of hepatic steatosis (≥5%, ≥15%, and ≥25% fat content). The results demonstrated strong diagnostic performance, with TAI™ achieving AUC values of 0.917, 0.914, and 0.898 for mild, moderate, and severe steatosis, respectively. TSI™ similarly showed robust performance.
The study also established optimal cutoff values for TAI™ and TSI™ parameters to guide staging of hepatic steatosis, offering high sensitivity and specificity. These findings suggest that Samsung’s RS85 Prestige QUS technologies can serve as reliable, noninvasive tools for liver fat quantification, providing clinicians with an accessible alternative to MRI for NAFLD assessment.
For step-by-step instructions on how to perform TAI™ examinations using the RS85 Prestige system, refer to the TAI™ Workflow Guide.
