Utility of S-Shearwave Imaging™ for the prediction of prostate cancer

Urology, Prof. Chan Kyo Kim, White Paper, S-Shearwave™ Imaging, RS85 Prestige, RS85 Prestige-urology

This white paper presents a prospective clinical study evaluating S-Shearwave Imaging™, Samsung Medison’s advanced ultrasound elastography technology, for improving prostate cancer diagnosis. The study assessed the diagnostic performance of 2D-Shear Wave Elastography (2D-SWE) using the RS85 Prestige system in 38 men with elevated PSA levels and/or suspicious MRI findings.

Using transrectal ultrasound (TRUS), S-Shearwave Imaging™ was applied to evaluate tissue stiffness across 12 prostate sectors. Quantitative elasticity metrics—including maximum (Emax), mean (Emean), and minimum (Emin) Young’s modulus values—were analyzed against biopsy-confirmed results. The study found that stiffness values were significantly higher in cancer-positive regions compared to benign tissues across both patient-based and region-based analyses.

In patient-based analysis, Emean demonstrated the highest diagnostic performance (AUC: 0.840), with 100% specificity and 70.6% sensitivity at a 41.3 kPa cutoff. For predicting clinically significant cancer (CSC), Emax showed the best AUC (0.865), with 84.6% sensitivity and 92.0% specificity at a 52.4 kPa cutoff. Region-based results confirmed SWE’s effectiveness in differentiating benign from malignant tissue, with moderate-to-good interobserver reliability.

S-Shearwave Imaging™ also proved valuable in guiding targeted prostate biopsies, especially when MRI and ultrasound findings were misaligned or unclear. Its real-time stiffness data improves localization accuracy during prostate cancer evaluation and supports clinical decision-making.

For step-by-step clinical use, visit the S-Shearwave Imaging™ Workflow Guide with RS85 Prestige .

Urology, Prof. Chan Kyo Kim, White Paper, S-Shearwave™ Imaging, RS85 Prestige, RS85 Prestige, RS85 Prestige
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Prof. Chan Kyo Kim

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Urology

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RS85 Prestige

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S-Shearwave™ Imaging
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